Reassessment of Data Used in Setting Exposure Limits for Hot Particles
نویسندگان
چکیده
منابع مشابه
Strategies for setting occupational exposure limits for particles.
To set occupational exposure limits (OELs) for aerosol particles, dusts, or chemicals, one has to evaluate whether mechanistic considerations permit identification of a no observed effect level (NOEL). In the case of carcinogenic effects, this can be assumed if no genotoxicity is involved, and exposure is considered safe if it does not exceed the NOEL. If tumor induction is associated with geno...
متن کاملReassessment of occupational exposure limits.
BACKGROUND Although the Netherlands currently has its own procedure for evaluating chemical compounds and setting occupational exposure limits (OELs), most of these limits were originally adopted in the 1970s from threshold limit values (TLVs) set by the American Conference of Governmental Industrial Hygienists (ACGIH). However, beginning in the late 1980s, criticism about non-scientific consid...
متن کاملSetting Occupational Exposure Limits: Are
Setting limits for safe exposure to toxic agents in the workplace is a complex process involving science, law, and policy. Development and use of occupational exposure limits (OELs) transcends national interests and international borders. Even though OELs have a lengthy history, and they form the cornerstone of most occupational risk assessment and risk management plans, their effectiveness in ...
متن کاملThe Scientific Basis of Uncertainty Factors Used in Setting Occupational Exposure Limits
The uncertainty factor concept is integrated into health risk assessments for all aspects of public health practice, including by most organizations that derive occupational exposure limits. The use of uncertainty factors is predicated on the assumption that a sufficient reduction in exposure from those at the boundary for the onset of adverse effects will yield a safe exposure level for at lea...
متن کاملAn Overview of Setting Occupational Exposure Limits (OELs) for Pharmaceuticals
Introduction Occupational exposure limits (OELs) 1 for the protection of workers have been around at least since 1939 when the National (later changed to American) Conference of Governmental Industrial Hygienists (ACGIH) published its inaugural acceptable workplace exposure limits (now known as threshold limit values, or TLVs). In 1970, the U. S. Occupational Safety and Health Act incorporated ...
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ژورنال
عنوان ژورنال: Radiation Protection Dosimetry
سال: 1991
ISSN: 1742-3406,0144-8420
DOI: 10.1093/oxfordjournals.rpd.a081115